PGRMC1 has been reported to interact with multiple proteins including Insig-1, SCAP, P450 proteins, PAIR-BP1, and epidermal growth factor (EGFR)[29C33]. of siramesine, a generally accepted MMV008138 sigma-2 agonist, we have categorized our sigma-2 ligands into agonists, partial agonists, and antagonists. … Continue reading PGRMC1 has been reported to interact with multiple proteins including Insig-1, SCAP, P450 proteins, PAIR-BP1, and epidermal growth factor (EGFR)[29C33]